# MyGene.info

> Look up genes in MyGene.info, which combines NCBI Gene, Ensembl, UniProt and more: search genes in human, mouse and other species, get one or many by ID, match a list of symbols, and read a gene's Gene Ontology terms, pathways and orthologs.

App · 9 actions. Web page: https://docs.lodol.com/docs/integrations/mygene

## Actions

### Find the same gene in other species

Find a gene's orthologs, its counterparts in other species, such as the mouse or zebrafish version of a human gene, with their IDs, symbols and names.

**Inputs**

- Gene ID (`gene_id`, text, required): The gene's NCBI Gene ID, such as 1017 for human CDK2, or its Ensembl gene ID, such as ENSG00000123374. Search genes finds the ID from a symbol.
- Source (`source`, text): Where orthologs come from. The Alliance is current and says how many methods agree; HomoloGene covers more species but stopped updating in 2014. One of: `agr` (Alliance of Genome Resources (current, model organisms)), `homologene` (NCBI HomoloGene (more species, last updated 2014)). Default: `agr`.
- Only these species (`species`, list): Keep only orthologs in these species. Choose none for all. One or more of: `human` (Human (Homo sapiens)), `mouse` (Mouse (Mus musculus)), `rat` (Rat (Rattus norvegicus)), `zebrafish` (Zebrafish (Danio rerio)), `fruitfly` (Fruit fly (Drosophila melanogaster)), `nematode` (Nematode worm (Caenorhabditis elegans)), `thale-cress` (Thale cress (Arabidopsis thaliana)), `frog` (Frog (Xenopus tropicalis)), `pig` (Pig (Sus scrofa)).

**Outputs**

- `count` (number): How many came back in this step
- `gene_id` (text): MyGene.info's ID for the gene: its NCBI Gene ID, or its Ensembl ID when it has none
- `orthologs` (list): The same gene in other species
- `source` (text): Where the orthologs come from: agr or homologene
- `species` (text): The species in plain words, such as human or mouse; empty for a less common one
- `symbol` (text): The official gene symbol, such as CDK2

**Example output**

```json
{
  "count": 4,
  "gene_id": "1017",
  "orthologs": [
    {
      "best_match": true,
      "gene_id": "852457",
      "methods_agreeing": 8,
      "methods_total": 9,
      "name": "cyclin-dependent serine/threonine-protein kinase CDC28",
      "species": "baker's yeast",
      "symbol": "CDC28",
      "taxonomy_id": 559292,
      "url": "https://www.ncbi.nlm.nih.gov/gene/852457"
    },
    {
      "best_match": true,
      "gene_id": "493498",
      "methods_agreeing": 5,
      "methods_total": 9,
      "name": "cyclin-dependent kinase 2",
      "species": "frog",
      "symbol": "cdk2",
      "taxonomy_id": 8364,
      "url": "https://www.ncbi.nlm.nih.gov/gene/493498"
    },
    {
      "best_match": true,
      "gene_id": "399314",
      "methods_agreeing": 1,
      "methods_total": 1,
      "name": "cyclin-dependent kinase 2 S homeolog",
      "species": "African clawed frog",
      "symbol": "cdk2.S",
      "taxonomy_id": 8355,
      "url": "https://www.ncbi.nlm.nih.gov/gene/399314"
    },
    {
      "best_match": true,
      "gene_id": "432036",
      "methods_agreeing": 1,
      "methods_total": 1,
      "name": "cyclin-dependent kinase 2 L homeolog",
      "species": "African clawed frog",
      "symbol": "cdk2.L",
      "taxonomy_id": 8355,
      "url": "https://www.ncbi.nlm.nih.gov/gene/432036"
    }
  ],
  "source": "agr",
  "species": "human",
  "symbol": "CDK2"
}
```

### Get a gene

Get a gene's symbol, name and summary, its other names, where it is in the genome, and its IDs in NCBI Gene, Ensembl, UniProt, HGNC, OMIM and RefSeq.

**Inputs**

- Gene ID (`gene_id`, text, required): The gene's NCBI Gene ID, such as 1017 for human CDK2, or its Ensembl gene ID, such as ENSG00000123374. Search genes finds the ID from a symbol.
- Extra fields (`extra_fields`, list): More of each gene's record to return, under fields: such as pathway, go.BP, pdb, exons or interpro. List available fields describes them all.

**Outputs**

- `aliases` (list): Other symbols the gene has gone by
- `chromosome` (text): The chromosome it is on
- `end` (number): Where it ends on the chromosome
- `ensembl_gene_id` (text): Ensembl gene ID, such as ENSG00000123374
- `ensembl_gene_ids` (list): Every Ensembl gene ID linked to it
- `entrez_id` (text): NCBI Gene (Entrez) ID, such as 1017
- `fields` (object): The Extra fields asked for, by name (such as go.BP), as MyGene.info gives them
- `gene_id` (text): MyGene.info's ID for the gene: its NCBI Gene ID, or its Ensembl ID when it has none
- `hgnc_id` (text): HGNC ID, for human genes, such as HGNC:1771
- `map_location` (text): Its cytogenetic band, such as 12q13.2
- `name` (text): The gene's full name
- `omim_id` (text): OMIM ID, for human genes
- `other_names` (list): Other full names
- `refseq_protein` (list): RefSeq protein IDs (NP_, XP_)
- `refseq_rna` (list): RefSeq transcript IDs (NM_, NR_, XM_)
- `species` (text): The species in plain words, such as human or mouse; empty for a less common one
- `start` (number): Where it starts on the chromosome (current genome build)
- `strand` (number): 1 for the forward strand, -1 for the reverse
- `summary` (text): What the gene does, from NCBI's RefSeq summary
- `symbol` (text): The official gene symbol, such as CDK2
- `taxonomy_id` (number): The species' NCBI taxonomy ID, such as 9606 for human
- `type` (text): Kind of gene, such as protein-coding or ncRNA
- `uniprot_id` (text): Its reviewed UniProt (Swiss-Prot) accession, such as P24941
- `url` (text): The gene's page at NCBI Gene (or Ensembl)

**Example output**

```json
{
  "aliases": [
    "CDKN2",
    "p33(CDK2)"
  ],
  "chromosome": "12",
  "end": 55972789,
  "ensembl_gene_id": "ENSG00000123374",
  "ensembl_gene_ids": [
    "ENSG00000123374"
  ],
  "entrez_id": "1017",
  "fields": {},
  "gene_id": "1017",
  "hgnc_id": "HGNC:1771",
  "map_location": "12q13.2",
  "name": "cyclin dependent kinase 2",
  "omim_id": "116953",
  "other_names": [
    "cdc2-related protein kinase",
    "cell division protein kinase 2",
    "cyclin-dependent kinase 2",
    "p33 protein kinase"
  ],
  "refseq_protein": [
    "NP_001277159.1",
    "NP_001789.2",
    "NP_439892.2",
    "XP_011536034.1"
  ],
  "refseq_rna": [
    "NM_001290230.2",
    "NM_001798.5",
    "NM_052827.4",
    "XM_011537732.2"
  ],
  "species": "human",
  "start": 55966781,
  "strand": 1,
  "summary": "This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other\u2026",
  "symbol": "CDK2",
  "taxonomy_id": 9606,
  "type": "protein-coding",
  "uniprot_id": "P24941",
  "url": "https://www.ncbi.nlm.nih.gov/gene/1017"
}
```

### Get a gene's Gene Ontology terms

List what a gene does, where its product works in the cell and which processes it takes part in, as Gene Ontology terms with their evidence codes and papers.

**Inputs**

- Gene ID (`gene_id`, text, required): The gene's NCBI Gene ID, such as 1017 for human CDK2, or its Ensembl gene ID, such as ENSG00000123374. Search genes finds the ID from a symbol.
- Categories (`categories`, list): Which kinds of term to list. Choose none for all three. One or more of: `BP` (Biological process), `MF` (Molecular function), `CC` (Cellular component).

**Outputs**

- `biological_process` (number): Biological process terms
- `cellular_component` (number): Cellular component terms
- `count` (number): How many came back in this step
- `gene_id` (text): MyGene.info's ID for the gene: its NCBI Gene ID, or its Ensembl ID when it has none
- `molecular_function` (number): Molecular function terms
- `species` (text): The species in plain words, such as human or mouse; empty for a less common one
- `symbol` (text): The official gene symbol, such as CDK2
- `terms` (list): Gene Ontology terms, one row each

**Example output**

```json
{
  "biological_process": 0,
  "cellular_component": 0,
  "count": 4,
  "gene_id": "1017",
  "molecular_function": 4,
  "species": "human",
  "symbol": "CDK2",
  "terms": [
    {
      "category": "molecular function",
      "evidence_codes": [
        "IEA"
      ],
      "id": "GO:0000287",
      "pubmed_ids": [],
      "qualifiers": [
        "enables"
      ],
      "term": "magnesium ion binding"
    },
    {
      "category": "molecular function",
      "evidence_codes": [
        "IEA"
      ],
      "id": "GO:0004672",
      "pubmed_ids": [],
      "qualifiers": [
        "enables"
      ],
      "term": "protein kinase activity"
    },
    {
      "category": "molecular function",
      "evidence_codes": [
        "IDA",
        "IEA",
        "IGI"
      ],
      "id": "GO:0004674",
      "pubmed_ids": [
        11953320,
        26996940
      ],
      "qualifiers": [
        "enables"
      ],
      "term": "protein serine/threonine kinase activity"
    },
    {
      "category": "molecular function",
      "evidence_codes": [
        "IBA",
        "IDA",
        "IEA",
        "TAS"
      ],
      "id": "GO:0004693",
      "pubmed_ids": [
        21596315,
        24728993,
        28216226
      ],
      "qualifiers": [
        "enables"
      ],
      "term": "cyclin-dependent protein serine/threonine kinase activity"
    }
  ]
}
```

### Get a gene's pathways

List the pathways a gene takes part in, from KEGG, Reactome, WikiPathways, BioCarta and other pathway databases, with links.

**Inputs**

- Gene ID (`gene_id`, text, required): The gene's NCBI Gene ID, such as 1017 for human CDK2, or its Ensembl gene ID, such as ENSG00000123374. Search genes finds the ID from a symbol.

**Outputs**

- `count` (number): How many came back in this step
- `gene_id` (text): MyGene.info's ID for the gene: its NCBI Gene ID, or its Ensembl ID when it has none
- `pathways` (list): Pathways the gene takes part in
- `sources` (list): The databases the pathways come from
- `species` (text): The species in plain words, such as human or mouse; empty for a less common one
- `symbol` (text): The official gene symbol, such as CDK2

**Example output**

```json
{
  "count": 5,
  "gene_id": "1017",
  "pathways": [
    {
      "id": "cellcyclepathway",
      "name": "cyclins and cell cycle regulation",
      "source": "BioCarta",
      "url": null
    },
    {
      "id": "hsa04068",
      "name": "FoxO signaling pathway - Homo sapiens (human)",
      "source": "KEGG",
      "url": "https://www.kegg.jp/pathway/hsa04068"
    },
    {
      "id": "Pathway_BCR",
      "name": "BCR",
      "source": "NetPath",
      "url": null
    },
    {
      "id": "atr_pathway",
      "name": "ATR signaling pathway",
      "source": "PID",
      "url": null
    },
    {
      "id": "WP1530",
      "name": "miRNA regulation of DNA damage response",
      "source": "WikiPathways",
      "url": "https://www.wikipathways.org/pathways/WP1530"
    }
  ],
  "sources": [
    "BioCarta",
    "KEGG",
    "NetPath",
    "PID",
    "WikiPathways"
  ],
  "species": "human",
  "symbol": "CDK2"
}
```

### Get database information

Get which release of MyGene.info is live and when it was built, how many genes and species it holds, the genome builds its positions use, and the version of each source database.

**Inputs**: None.

**Outputs**

- `build_date` (text): When it was built (YYYY-MM-DD)
- `build_version` (text): The data release, such as 20260922
- `ensembl_genes` (number): Genes with an Ensembl ID
- `entrez_genes` (number): Genes with an NCBI Gene ID
- `genome_assemblies` (list): Genome builds used for positions
- `source_count` (number): How many came back in this step
- `sources` (list): The databases MyGene.info draws on
- `total_genes` (number): Genes in all
- `total_species` (number): Species covered

**Example output**

```json
{
  "build_date": "2026-09-22",
  "build_version": "20260922",
  "ensembl_genes": 122757589,
  "entrez_genes": 72623559,
  "genome_assemblies": [
    {
      "assembly": "hg38",
      "species": "human",
      "taxonomy_id": 9606
    },
    {
      "assembly": "mm39",
      "species": "mouse",
      "taxonomy_id": 10090
    },
    {
      "assembly": "rn6",
      "species": "rat",
      "taxonomy_id": 10116
    },
    {
      "assembly": "dm6",
      "species": "fruitfly",
      "taxonomy_id": 7227
    }
  ],
  "source_count": 4,
  "sources": [
    {
      "downloaded": "2026-06-21",
      "license": null,
      "name": "ensembl",
      "url": null,
      "version": "116"
    },
    {
      "downloaded": "2026-09-20",
      "license": null,
      "name": "entrez",
      "url": null,
      "version": "20260919"
    },
    {
      "downloaded": "2026-09-22",
      "license": null,
      "name": "reactome",
      "url": null,
      "version": "97"
    },
    {
      "downloaded": "2026-09-08",
      "license": null,
      "name": "uniprot",
      "url": null,
      "version": "20260903"
    }
  ],
  "total_genes": 94312900,
  "total_species": 54000
}
```

### Get several genes

Get up to 1,000 genes by ID in one step, each with the same details as Get a gene. IDs MyGene.info does not know are listed separately.

**Inputs**

- Gene IDs (`gene_ids`, list, required): NCBI Gene or Ensembl IDs: a list from an earlier step, or IDs separated by commas or new lines, such as 1017, 7157.
- Extra fields (`extra_fields`, list): More of each gene's record to return, under fields: such as pathway, go.BP, pdb, exons or interpro. List available fields describes them all.

**Outputs**

- `count` (number): How many came back in this step
- `genes` (list): The genes found, in the order asked
- `not_found` (list): IDs MyGene.info does not know

**Example output**

```json
{
  "count": 2,
  "genes": [
    {
      "aliases": [
        "CDKN2",
        "p33(CDK2)"
      ],
      "chromosome": "12",
      "end": 55972789,
      "ensembl_gene_id": "ENSG00000123374",
      "ensembl_gene_ids": [
        "ENSG00000123374"
      ],
      "entrez_id": "1017",
      "fields": {},
      "gene_id": "1017",
      "hgnc_id": "HGNC:1771",
      "map_location": "12q13.2",
      "name": "cyclin dependent kinase 2",
      "omim_id": "116953",
      "other_names": [
        "cdc2-related protein kinase",
        "cell division protein kinase 2",
        "cyclin-dependent kinase 2",
        "p33 protein kinase"
      ],
      "refseq_protein": [
        "NP_001277159.1",
        "NP_001789.2",
        "NP_439892.2",
        "XP_011536034.1"
      ],
      "refseq_rna": [
        "NM_001290230.2",
        "NM_001798.5",
        "NM_052827.4",
        "XM_011537732.2"
      ],
      "species": "human",
      "start": 55966781,
      "strand": 1,
      "summary": "This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other\u2026",
      "symbol": "CDK2",
      "taxonomy_id": 9606,
      "type": "protein-coding",
      "uniprot_id": "P24941",
      "url": "https://www.ncbi.nlm.nih.gov/gene/1017"
    },
    {
      "aliases": [
        "BCC7",
        "BMFS5",
        "LFS1",
        "P53"
      ],
      "chromosome": "17",
      "end": 7687546,
      "ensembl_gene_id": "ENSG00000141510",
      "ensembl_gene_ids": [
        "ENSG00000141510"
      ],
      "entrez_id": "7157",
      "fields": {},
      "gene_id": "7157",
      "hgnc_id": "HGNC:11998",
      "map_location": "17p13.1",
      "name": "tumor protein p53",
      "omim_id": "191170",
      "other_names": [
        "antigen NY-CO-13",
        "cellular tumor antigen p53",
        "mutant tumor protein 53",
        "phosphoprotein p53"
      ],
      "refseq_protein": [
        "NP_000537.3",
        "NP_001119584.1",
        "NP_001119585.1",
        "NP_001119586.1"
      ],
      "refseq_rna": [
        "NM_000546.6",
        "NM_001126112.3",
        "NM_001126113.3",
        "NM_001126114.3"
      ],
      "species": "human",
      "start": 7661779,
      "strand": -1,
      "summary": "This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers,\u2026",
      "symbol": "TP53",
      "taxonomy_id": 9606,
      "type": "protein-coding",
      "uniprot_id": "P04637",
      "url": "https://www.ncbi.nlm.nih.gov/gene/7157"
    }
  ],
  "not_found": [
    "ZZZ"
  ]
}
```

### List available fields

List the fields a gene record can have, such as go.BP or pathway.kegg, to use in Extra fields or to search one field.

**Inputs**

- Name contains (`search`, text): Only fields whose name contains this, such as go or pathway.

**Outputs**

- `count` (number): How many came back in this step
- `fields` (list): Fields found

**Example output**

```json
{
  "count": 4,
  "fields": [
    {
      "name": "go.BP",
      "searchable": true,
      "searched_by_default": false,
      "type": "object"
    },
    {
      "name": "go.BP.category",
      "searchable": true,
      "searched_by_default": false,
      "type": "keyword"
    },
    {
      "name": "go.BP.evidence",
      "searchable": true,
      "searched_by_default": false,
      "type": "keyword"
    },
    {
      "name": "go.BP.id",
      "searchable": true,
      "searched_by_default": true,
      "type": "keyword"
    }
  ]
}
```

### Look up a list of genes

Turn a list of up to 1,000 symbols or IDs, such as a spreadsheet column, into genes: one row per match with its IDs, name and species. Names that match nothing, or more than one gene, are listed separately.

**Inputs**

- Genes to look up (`names`, list, required): Symbols or IDs: a list from an earlier step, or text with one per line or separated by commas, such as CDK2, TP53.
- Match by (`match_by`, list): What the list holds. Choose more than one if it is mixed. Gene symbol is used when none is chosen. One or more of: `symbol` (Gene symbol, such as CDK2), `alias` (Other or former symbol), `entrezgene` (NCBI Gene ID, such as 1017), `ensembl.gene` (Ensembl gene ID, such as ENSG00000123374), `uniprot` (UniProt accession, such as P24941), `refseq` (RefSeq ID, such as NM_001798), `name` (Full gene name), `reporter` (Microarray probe ID). Default: `["symbol"]`.
- Species (`species`, list): Which species to look in. Choose none to look in every species. One or more of: `human` (Human (Homo sapiens)), `mouse` (Mouse (Mus musculus)), `rat` (Rat (Rattus norvegicus)), `zebrafish` (Zebrafish (Danio rerio)), `fruitfly` (Fruit fly (Drosophila melanogaster)), `nematode` (Nematode worm (Caenorhabditis elegans)), `thale-cress` (Thale cress (Arabidopsis thaliana)), `frog` (Frog (Xenopus tropicalis)), `pig` (Pig (Sus scrofa)). Default: `["human"]`.
- Other species (taxonomy IDs) (`other_species`, text): Any other species, as NCBI taxonomy IDs separated by commas, such as 9913 for cow or 9615 for dog.
- Best match only (`best_match_only`, true/false): Keep only the best gene for each name. Turn off to get every gene a name matches, such as the same symbol in several species. Default: `true`.
- Extra fields (`extra_fields`, list): More of each gene's record to return, under fields: such as pathway, go.BP, pdb, exons or interpro. List available fields describes them all.

**Outputs**

- `count` (number): How many came back in this step
- `matches` (list): One row per match, in the order asked
- `multiple_matches` (list): Names or IDs that matched more than one gene
- `not_found` (list): Names or IDs that matched no gene
- `species` (text): The species searched, as names and taxonomy IDs, or 'all'

**Example output**

```json
{
  "count": 2,
  "matches": [
    {
      "chromosome": "12",
      "ensembl_gene_id": "ENSG00000123374",
      "entrez_id": "1017",
      "fields": {},
      "gene_id": "1017",
      "name": "cyclin dependent kinase 2",
      "query": "CDK2",
      "score": 17.3438,
      "species": "human",
      "symbol": "CDK2",
      "taxonomy_id": 9606,
      "type": "protein-coding",
      "url": "https://www.ncbi.nlm.nih.gov/gene/1017"
    },
    {
      "chromosome": "17",
      "ensembl_gene_id": "ENSG00000141510",
      "entrez_id": "7157",
      "fields": {},
      "gene_id": "7157",
      "name": "tumor protein p53",
      "query": "TP53",
      "score": 17.9644,
      "species": "human",
      "symbol": "TP53",
      "taxonomy_id": 9606,
      "type": "protein-coding",
      "url": "https://www.ncbi.nlm.nih.gov/gene/7157"
    }
  ],
  "multiple_matches": [],
  "not_found": [
    "NOTAGENE"
  ],
  "species": "human"
}
```

### Search genes

Find genes by symbol, name, words, an ID from another database, or a chromosome region, in the species you choose, best match first.

**Inputs**

- Search for (`query`, text, required): A symbol such as CDK2, words such as insulin receptor, an ID, or a region such as chr12:55,966,000-55,973,000. To search one field, name it: symbol:CDK* or pdb:1HCK.
- Species (`species`, list): Which species to look in. Choose none to look in every species. One or more of: `human` (Human (Homo sapiens)), `mouse` (Mouse (Mus musculus)), `rat` (Rat (Rattus norvegicus)), `zebrafish` (Zebrafish (Danio rerio)), `fruitfly` (Fruit fly (Drosophila melanogaster)), `nematode` (Nematode worm (Caenorhabditis elegans)), `thale-cress` (Thale cress (Arabidopsis thaliana)), `frog` (Frog (Xenopus tropicalis)), `pig` (Pig (Sus scrofa)). Default: `["human"]`.
- Other species (taxonomy IDs) (`other_species`, text): Any other species, as NCBI taxonomy IDs separated by commas, such as 9913 for cow or 9615 for dog.
- Extra fields (`extra_fields`, list): More of each gene's record to return, under fields: such as pathway, go.BP, pdb, exons or interpro. List available fields describes them all.
- Max results (`max_results`, number): Return at most this many genes. From 1 to 1000. Default: `10`.
- Skip (`skip`, number): Leave out this many genes from the start, to get the next page. MyGene.info pages up to 10,000 results. From 0 to 9999. Default: `0`.

**Outputs**

- `count` (number): How many came back in this step
- `genes` (list): Genes found, best match first
- `has_more` (true/false): Whether more are left after these (raise Skip to get them)
- `query` (text): What was searched for
- `species` (text): The species searched, as names and taxonomy IDs, or 'all'
- `total` (number): How many genes match in all

**Example output**

```json
{
  "count": 2,
  "genes": [
    {
      "chromosome": "12",
      "ensembl_gene_id": "ENSG00000123374",
      "entrez_id": "1017",
      "fields": {
        "pdb": [
          "1AQ1",
          "1B38",
          "1B39",
          "1BUH"
        ]
      },
      "gene_id": "1017",
      "name": "cyclin dependent kinase 2",
      "score": 138.7505,
      "species": "human",
      "symbol": "CDK2",
      "taxonomy_id": 9606,
      "type": "protein-coding",
      "url": "https://www.ncbi.nlm.nih.gov/gene/1017"
    },
    {
      "chromosome": "10",
      "ensembl_gene_id": "ENSMUSG00000025358",
      "entrez_id": "12566",
      "fields": {
        "pdb": null
      },
      "gene_id": "12566",
      "name": "cyclin dependent kinase 2",
      "score": 116.3714,
      "species": "mouse",
      "symbol": "Cdk2",
      "taxonomy_id": 10090,
      "type": "protein-coding",
      "url": "https://www.ncbi.nlm.nih.gov/gene/12566"
    }
  ],
  "has_more": true,
  "query": "CDK2",
  "species": "human,mouse",
  "total": 24
}
```